Found 19 matching trials
Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors PHASE2 This phase II trial studies how well olaparib and ceralasertib (AZD6738) wo...
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Location
University of Alabama at Birmingham Cancer Center
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DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer PHASE2 To assess the effect of AZD6738 and Durvalumab combination or AZD6738 and O...
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Seoul National University Hospital
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A Study to Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC). PHASE1 This biomarker study has been designed to assess the effects of different a...
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ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no Loss PHASE2 ATARI trial tests the ATR inhibitor drug ceralasertib (AZD6738) alone and i...
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Location
The Ottawa Hospital Cancer Centre
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Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors PHASE2 This phase II trial studies how well ceralasertib, am Ataxia telangiectasia...
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Location
City of Hope Comprehensive Cancer Center
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AMTEC IIT: Phase 2 Multiarm Study in TNBC PHASE2 This phase II study assesses the efficacy of the combination of olaparib wi...
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OHSU Knight Cancer Institute
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Targeting Resistant Prostate Cancer With ATR and PARP Inhibition (TRAP Trial) PHASE2 The purpose of this study is to test the effectiveness (how well the drugs ...
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Location
University of Michigan Hospital
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Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy PHASE2 This is an open-label, multi-centre, umbrella Phase II study in participant...
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Combination ATR and PARP Inhibitor (CAPRI) Trial With AZD6738 and Olaparib in Recurrent Ovarian Cancer PHASE2 Investigational agent, AZD6738 will be given in combination with Olaparib t...
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Johns Hopkins University School of Medicine
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The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial PHASE2 plasmaMATCH is a multi-centre phase IIa umbrella trial platform consisting ...
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Royal Marsden Hosital
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